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Stuttgart Incentives

The virus has more secrets to reveal

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United Secondary and Vocational School Vocational School Polytechnical School Polytechnic Royal College of Technology College of Technology Universität Stuttgart

The beginning of the beginning: In search of the trigger for virus reproduction

Back to the question that virus research had been dealing with from the very beginning: What is a virus?

The insight that the information for virus replication is contained in ribonucleic acid (RNA) suggested that there must be some interaction between the virus and the host cell. Viruses lack one particular thing: they don't have a mechanism that reads their own information and converts it into protein structures. For this reason they have to use the translation mechanisms of a cell on the ribosomes. The virus is thus unlike either a protein molecule with its “chemical” replication or an organism with its own metabolism.
The nature of a virus can thus be described by reference to its particularly parasitic way of reproducing.

From the late 1970s to the early 1990s, work groups associated with Mundry dealt with the first step in virus replication. They were in particularly close contact with groups in Strasbourg and England.

Further information for experts: Stuttgart's contributions to understanding the replication trigger

 

Start of chapter Next section
The university gets the bug
The virus on its way to Germany
A stopover in Tübingen
A university makes plans
The virus has more secrets to reveal
  The beginning of the beginning
  Committing suicide in order to survive
  The tobacco mosaic virus gets company
The virus takes to the air
"Wonderful street-car meeting"
A virus isn't that easy to get rid of
Biography: Karl-Wolfgang Mundry
Incentive timeline