IBC University Stuttgart

 

 

 

 

 

 

Yeast strain design and modelling

"Take two stone tablets and carve on one of them: Problems are inevitable. And on the other carve: Problems are soluble."
– David Deutsch (TED: Ideas worth spreading)

We design yeast strains appropriate for systems biology solutions. Currently, strains are developed, which enable external control of the cell division cycle. For this purpose yeast cells are modified in a way that mitotic checkpoints can bidirectionally governed through minimal-invasive, externally triggered regulation of gene transcription. These means will allow permanent synchronization of yeast cultures as well as in silico model based modification of cell cycle programming.