Learning from yeast

We study the chemistry of cellular systems on selected processes important for life of the yeast Saccharomyces cerevisiae

 

Main Topics

Functions of the ubiquitin/proteasome system in regulation of cell metabolism, in protein quality control in the cytoplasm and in the endoplasmatic reticulum, in cell cycle and programmed cell death ("apoptosis")

Molecular mechanisms of endocytosis and endosome biogenesis

Functions of Ca2+ and Mn2+ in secretory organelles and as inducers of apoptosis

Reconstruction of cellular networks ("systems biology ")