Prof. Dr. Christina Wege

Prof. Dr. Christina Wege
Telefon	0049 711 685-65073
Telefax	0049 711 685-65096
Zimmer	9-558
E-Mail	Link
Adresse	Universität Stuttgart Biologisches Insitut, Abt. Molekularbiologie Pfaffenwaldring 57 70569 Stuttgart Deutschland
Sprechstunde	Students' Counseling Thu (Do) 10.30-11.30

Research

a) Geminiviruses: Molecular biology of viral plant diseases, resistance mechanisms, interactions of plants and viruses in single and mixed infections b) Biomaterials and nanobiotechnology: Virus-derived biotemplates for nanostructured hybrid materials and building-blocks in analytical, technical & therapeutic applications

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Publications

• Balci, S., Hahn, K., Kopold, P., Kadri, A., Wege, C., Kern, K., and A.M. Bittner. 2012. Electroless synthesis of 3 nm wide alloy nanowires inside Tobacco mosaic virus. Nanotechnology, 23, 045603 (7pp).
   
• Atanasova, P., Rothenstein, D., Schneider, J. J., Hoffmann, R. C., Dilfer, S., Eiben, S., Wege, C., Jeske, H. & Bill, J. (2011). Virus-templated synthesis of ZnO nanostructures and formation of field-effect transistors. Adv. Mat. , 23, 4918-4922.
   
• Cremer, C., Kaufmann, R., Gunkel, M., Pres, S., Weiland, Y., Mueller, P., Ruckelshausen, T., Lemmer, P., Geiger, F., Degenhard, S., Wege, C., Lemmermann, N. A. W., Holtappels, R., Strickfaden, H. & Hausmann, M. (2011). Superresolution imaging of biological nanostructures by Spectral Precision Distance Microscopy (SPDM). Biotechnol. J.,6, 1037-1051.
   
• Sardo, L., Wege, C., Kober, S., Kocher, C., Accotto, G. P. & Noris, E. (2011). RNA viruses and their silencing suppressors boost Abutilon mosaic virus, but not the Old World Tomato yellow leaf curl Sardinia virus. Virus Res., 161. 170-180
   
• Mueller, A., Eber, F. J., Azucena, C., Petershans, A., Bittner, A. M., Gliemann, H., Jeske, H., and Wege, C. (2011). Inducible site-selective bottom-up assembly of virus-derived nanotube arrays on RNA-equipped wafers. ACS Nano 5, 4512-4520
   
• Kadri, A., Maiss, E., Amsharov, N., Bittner, A., Balci, S., Kern, K., Jeske, H., and Wege, C. (2011). Engineered tobacco mosaic virus mutants with distinct physical characteristics in planta and enhanced metallization properties. Virus Res. 157, 35-46.
   
• Wege, C., Jeske, H., Mueller, A., Eber, F.J., Kadri, A., Balci, S., Baralia, G., Amsharov, N., Petershans, A., Azucena, C., Gliemann, H., Thonke, K., Schirra, M., Wu, Z., Krill III, C., Bittner, A.M. (2011). Plant viral nanoscale biotemplates: From virowires to dumbbells and arrays. In "Nanotechnology - Fundamentals and Applications of Functional Nanostructures" (T. Schimmel, H. v. Löhneysen, and M. Barcewski, Eds.), ISBN 978-3-00-030810-9; pp. 383-407. Baden-Württemberg-Stiftung, Karlsruhe.
   
• Krenz, B., Windeisen, V., Wege, C., Jeske, H., and Kleinow, T. (2010). A plastid-targeted heat shock cognate 70 kDa protein interacts with the Abutilon mosaic virus movement protein. Virology 401, 6-17.
   
• Krenz, B., Wege, C., and Jeske, H. (2010). Cell-free construction of disarmed Abutilon mosaic virus-based gene silencing vectors. J. Virol. Methods 169, 129-137.
   
• Mueller, A., Kadri, A., Jeske, H., and Wege, C. (2010). In vitro assembly of Tobacco mosaic virus coat protein variants derived from fission yeast expression clones or plants. J. Virol. Methods 166, 77–85.
   
• Wu, Z., Mueller, A., Degenhard, S., Ruff, S. E., Geiger, F., Bittner, A., Wege, C. & Krill III, C. (2010). Enhancing the magnetoviscosity of ferrofluids by the addition of biological nanotubes. ACS Nano 4, 4531-4538.
   
• Wu, Z., Zierold, R., Mueller, A., Ruff, S. E., Ma, C., Khan, A. A., Geiger, F., Sommer, B. A., Knez, M., Nielsch, K., Bittner, A. M., Wege, C. & Krill III, C. (2010). Preparation and magnetoviscosity of nanotube ferrofluids by viral scaffolding and ALD on porous templates. Phys. Stat. Sol. B 247, 2412-2423.
   
• Balci, S., Bittner, A. M., Schirra, M., Thonke, K., Sauer, R., Hahn, K., Kadri, A., Wege, C., Jeske, H., and Kern, K. (2009). Catalytic coating of virus particles with zinc oxide. Electrochimica Acta 54, 5149-5154.
   
• Kleinow, T., Tanwir, F., Kocher, C., Krenz, B., Wege, C., and Jeske, H. (2009). Expression dynamics and ultrastructural localization of epitope-tagged Abutilon mosaic virus nuclear shuttle and movement proteins in Nicotiana benthamiana cells. Virology 391, 212-220.
   
• Wege, C. (2009). Mixed infections of geminiviruses and unrelated RNA viruses or viroids in tomato: a multitude of effects with a highly probable impact on epidemiology and agriculture. In Crop Plant Resistance to Biotic and Abiotic Factors: Current Potential and Future Demands, pp. 233-241. Edited by F. Feldmann, D. V. Alford & C. Furk. Braunschweig, Germany: Deutsche Phytomedizinische Gesellschaft.
   
• Balci, S., Leinberger, D. M., Knez, M., Bittner, A., Boes, F., Kadri, A., Wege, C., Jeske, H., and Kern, K. (2008). Printing and aligning mesoscale patterns of Tobacco mosaic viruses on surfaces. Adv. Mater. 20, 2195-2200.
   
• Jeske, H., Wege, C., Kern, K., and Bittner, A. (2008). Plant viral nanoscale biotemplates: on the road to virowires. In "Nanotechnology - Physics, Chemistry, and Biology of Functional Nanostructures" (T. Schimmel, H. v. Löhneysen, M. Barcewski, and C. Obermair, Eds.), Vol. 32, pp. 421-454. Landesstiftung Baden-Württemberg gGmbH, Karlsruhe.
   
• Kleinow, T., Holeiter, G., M., Nischang, Stein, M., Karayavuz, M., Wege, C., and Jeske, H. (2008). Post-translational modifications of Abutilon mosaic virus movement protein (BC1) in fission yeast. Virus Res. 131, 86-94.
   
• Balci, S., Noda, K., Bittner, A. M., Kadri, A., Wege, C., Jeske, H., and Kern, K. (2007). Self-assembly of metal-virus nanodumbbells. Angew. Chem. Int. Ed. 46(17), 3149-3151.
   
• Balci, S., Noda, K., Bittner, A. M., Kadri, A., Wege, C., Jeske, H., and Kern, K. (2007). Selbstorganisation von Metall-Virus-Nanohanteln. Angew. Chem. 119(17), 3210-3212.
   
• Frischmuth, S., Wege, C., Hülser, D., and Jeske, H. (2007). The movement protein BC1 promotes redirection of the nuclear shuttle protein BV1 of Abutilon mosaic geminivirus to the plasma membrane in fission yeast. Protoplasma 230, 117-123.
   
• Pohl, D., and Wege, C. (2007). Synergistic pathogenicity of a phloem-limited begomovirus and tobamoviruses despite negative interference. J. Gen. Virol. 88, 1034-1040.
   
• Wege, C. (2007). Movement and localization of Tomato yellow leaf curl viruses in the infected plant. In "Tomato yellow leaf curl virus disease" (H. Czosnek, Ed.), pp. 185-206. Springer, Dordrecht.
   
• Wege, C., and Pohl, D. (2007). Abutilon mosaic virus DNA B component supports mechanical virus transmission, but does not counteract begomoviral phloem limitation in transgenic plants. Virology 365, 173-186.
   
• Wege, C. & D. Siegmund (2007). Synergism of a DNA and an RNA virus: Enhanced tissue infiltration of the begomovirus Abutilon mosaic virus (AbMV) mediated by Cucumber mosaic virus (CMV). Virology 357, 10-28.
   
• Balci, S., Bittner, A. M., Hahn, K., Scheu, C., Knez, M., Kadri, A., Wege, W., Jeske, H., and Kern, K. (2006). Copper nanowires within the central channel of Tobacco mosaic virus particles. Electrochim. Acta 51, 6251-6257.
   
• Knez, M., Kadri, A., Wege, C., Gösele, U., Jeske, H., and Nielsch, K. (2006). Atomic layer deposition on biological macromolecules: Metal oxide coating of Tobacco mosaic virus and ferritin. Nano Letters 6, 1172-1177.
   
• aus dem Siepen, M., Pohl, J., Koo, B.-J., Wege, C., and Jeske, H. (2005). Poinsettia latent virus is not a cryptic virus, but a natural polerovirus-sobemovirus hybrid. Virology 336, 240-250.
   
• Frischmuth, S., Kleinow, T., Aberle, H.-J., Wege, C., Hülser, D., and Jeske, H. (2004). Yeast two-hybrid systems confirm the membrane-association and oligomerization of BC1 but do not detect an interaction of the movement proteins BC1 and BV1 of Abutilon mosaic geminivirus. Arch Virol 149, 2349-2364.
   
• Hehnle, S., Wege, C., and Jeske, H. (2004). The interaction of DNA with the movement proteins of geminiviruses revisited. J. Virol. 78, 7698-7706.
   
• Knez, M., Sumser, M., Bittner, A., Wege, C., and Jeske, H. (2004). Spatially selective nucleation of metal clusters on the tobacco mosaic virus. Adv. Funct. Mater. 14, 116-124.
   
• Knez, M., Sumser, M., Bittner, A., Wege, C., Jeske, H., Hoffmann, D. M. P., Kuhnke, K., and Kern, K. (2004). Binding the Tobacco mosaic virus to inorganic surfaces. Langmuir 20, 411-447.
   
• Morilla, G., Krenz, B., Jeske, H., Bejarano, E. R., and Wege, C. (2004). Tête à tête of Tomato yellow leaf curl virus (TYLCV) and Tomato yellow leaf curl Sardinia virus (TYLCSV) in single nuclei. J. Virol. 78, 10715–10723.
   
• Knez, M., Bittner, A., Boes, F., Wege, C., Jeske, H., Maiss, E., and Kern, K. (2003). Biotemplate synthesis of 3 nm nickel and cobalt nanowires. Nano Letters 3, 1079-1082.
   
• Aberle, H.-J., Rütz, M.-L., Karayavuz, M., Frischmuth, S., Wege, C., Hülser, D., and H. Jeske (2002): Localizing BC1 movement proteins of Abutilon mosaic geminivirus in yeasts by subcellular fractionation and freeze-fracture immuno-labelling. Arch. Virol. 147, 103-107.
   
• Knez, M., Sumser, M., Bittner, A., Wege, C., Jeske, H., Kooi, S., Burghard, M., and Kern, K. (2002). Electrochemical modification of individual nano-objects. J. Electroanalyt. Chem. 522, 70-74.
   
• Saunders, K., C. Wege, K. Veluthambi, H. Jeske, and J. Stanley (2001): The distinct disease phenotypes of the common and yellow vein strains of Tomato golden mosaic virus are determined by nucleotide differences in the 3'-terminal region of the gene encoding the movement protein. J. Gen. Virol. 82, 45-51.
   
• Wege, C., K. Saunders, J. Stanley, and H. Jeske (2001): Comparative analysis of tissue tropism of bipartite geminiviruses. J. Phytopathology 149, 359-368.
   
• Zhang, S.C., Wege, C., and H. Jeske (2001): Movement proteins (BC1 and BV1) of Abutilon mosaic geminivirus are cotransported in and between cells of sink but not of source leaves as detected by Green Fluorescent Protein tagging. Virology 290: 249-260.
   
• Wege, C., R.-D. Gotthardt, T. Frischmuth, and H. Jeske (2000): Fulfilling Koch's postulates for Abutilon mosaic virus. Arch. Virol. 145, 2217-2225.
   
• Wege, C. and H. Jeske (1998): Abutilon mosaic geminivirus proteins expressed and phosphorylated in Escherichia coli. J. Phytopathology 146, 613-621.
   

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Curriculum Vitae

Prof. Dr. Christina Wege *27.03.1966 in Pinneberg (Schleswig-Holstein), Germany

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Assignments & Responsibilities

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Teaching and Tuition

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